Airlines face thin profit margins, making even small changes to their operating costs a major challenge. One area of focus is reducing fuel consumption, as it is their largest individual expense. To achieve this, airlines invest in fuel-efficient aircraft with latest engines and materials. However, airlines can also improve fuel efficiency through design decisions, such as configuring aircraft seating and cabin layouts. Lightweight bioplastics, which can be used in interior components, hold promise in reducing operating costs. Bioplastics are already being used in some aircraft, but widespread adoption is hindered by the lack of large-scale production and affordable pricing. To become viable, bioplastics need to offer real cost benefits, such as reducing aircraft weight and increasing fuel efficiency. Regulatory hurdles have largely been cleared, with bioplastics deemed safe and fire-resistant for most non-structural components. If bioplastics can provide a significant cost savings, they could become a norm on commercial aircraft, supporting the industry’s goal of net-zero carbon emissions by 2050.